Week 3: Chargers Visit Bills Missing Both Tight Ends as Buffalo Comes Off Ten Days' Rest
The Los Angeles Chargers visit the Buffalo Bills on Sunday, September 27. Los Angeles is 0-2 after home losses to Arizona and Las Vegas, with Justin Herbert throwing two interceptions among three turnovers against the Raiders, and tight ends David Njoku and Charlie Kolar both went on injured reserve this week. Buffalo is 2-0 and has had ten days since beating Detroit 41-31, a game in which Josh Allen accounted for five touchdowns and James Cook III ran for 135 yards; D.J. Moore (shoulder) is day-to-day and Ed Oliver (hip) is being evaluated.
Herbert's turnovers
Three giveaways against Las Vegas in a game the Chargers outgained the Raiders; Buffalo's defense has faced two high-volume passers and allowed 62 points.
Buffalo's rest edge
Ten days off against a team traveling east; the Bills scored 27 in the first half against Detroit.
Jim Harbaugh at 0-2
Five of eight free-agent signings are hurt and the tight end room is Oronde Gadsden alone.
AI Prediction
Chargers 
Bills Allen at home against a depleted offense
Buffalo's offense has scored 77 points; the Chargers have scored 28 and just lost two starting tight ends.
Rest and travel
Ten days of rest against a team flying cross-country after consecutive losses.
Buffalo's defense is the soft spot
It allowed 31 to Houston and 31 to Detroit, which is why Los Angeles is projected to reach 17.
One of the week's two widest leans. The Chargers' path is a low-turnover game from Herbert and Omarion Hampton against a Bills defense that has been generous.
Bills Leaders
Chargers Leaders
Team Stats
| Chargers | Stat | Bills |
|---|---|---|
| 14.0 | Points Per Game | 38.5 |
| 304.5 | Total Yards | 435.5 |
| 200.5 | Yards Passing | 291.0 |
| 104.0 | Yards Rushing | 144.5 |
| 26.0 | Points Allowed Per Game | 31.0 |
| 351.5 | Yards Allowed | 395.5 |
| 265.0 | Pass Yards Allowed | 300.5 |
| 86.5 | Rush Yards Allowed | 95.0 |
Venue
Closing Line
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Bills Injuries