Week 5: Unbeaten 49ers Visit Seahawks in the First NFC West Showdown
The San Francisco 49ers visit the Seattle Seahawks on Sunday, October 11. San Francisco is 4-0 after a 24-14 win over Denver, with Brock Purdy throwing 11 touchdown passes in four games; Nick Bosa (calf), C.J. West, Kyle Juszczyk and three receivers are out and Marques Sigle and Upton Stout were hurt Sunday. Seattle is 3-1 after a 30-23 win over the Chargers in which Sam Darnold threw two touchdown passes and the defense forced four turnovers; the champions' only loss came on three turnovers at Washington.
San Francisco's attrition
Bosa, West, Juszczyk, Robinson, Stribling and Pearsall are all out.
Seattle at home
Three wins by 7 or more at Lumen Field and on the road.
Purdy's efficiency
Eleven touchdowns and three interceptions in four games.
AI Prediction
49ers 
Seahawks The injury list finally catches up to San Francisco
A defense without Bosa, West and possibly two defensive backs on the road against the champions.
San Francisco has not lost
Four wins by 10 or more, and Purdy is the most efficient quarterback in the league.
Seattle's defense forced four turnovers last week
The reason the model leans to the home team by a point.
A Low-confidence home lean in the week's closest call. The model's number has it 52-48.
Seahawks Leaders
49ers Leaders
Team Stats
| 49ers | Stat | Seahawks |
|---|---|---|
| 30.5 | Points Per Game | 26.3 |
| 389.0 | Total Yards | 359.3 |
| 251.8 | Yards Passing | 249.0 |
| 137.3 | Yards Rushing | 110.3 |
| 16.0 | Points Allowed Per Game | 18.3 |
| 314.5 | Yards Allowed | 263.3 |
| 214.8 | Pass Yards Allowed | 161.3 |
| 99.8 | Rush Yards Allowed | 102.0 |
Venue
Closing Line
Bet this matchup
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Seahawks Injuries